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Autism spectrum disorder (ASD) covers a range of
abnormalities. On one end of the spectrum is the severely autistic (“Rainman”
type) patient; while on the other is a person with attention deficit disorder
(ADHD). Persistent developmental delay (PDD) and Asperger’s Syndrome lie in
between. There has been a rapid and concerning increase in the incidence of ASD
to the point where one in 150 children born will be diagnosed with ASD. The
incidence is even higher in males at nearly one in 90. There has been much work
in the field of genetics to identify anomalies that may cause ASD. So far, over
one hundred genetic anomalies have been identified that are linked with ASD.
However, if genetics were the sole cause of ASD, we would not see the alarming
rise in its incidence. The rate of a solely genetic disorder should stay
constant over time. There is a much more sophisticated understanding of the
relationship between genes and environment that has come to the forefront—a
field called genomics. Genomics recognizes that the genetic blue print is only
a set of possibilities; it is the interaction of those genes with the
environment that determines how a person develops. With this in mind, a number
of pioneering physicians and research scientists have been looking at ASD to
find what environmental factors may play a role in the development of ASD and
whether manipulating these factors could reverse the process and actually cure a
child with ASD. This is known as the bio-medical approach to the treatment of
ASD and has been championed by groups such as Defeat Autism Now! (previously
known as DAN!). This approach is what we use at Bio Energy to treat our
patients who have been diagnosed with ASD.
The first are of interest lies in the digestive tract. It
has been known since autism was first described that most of these children have
issues with their digestion. These range from simple stomach upset and bloating
to severe, explosive diarrhea. Dietary changes frequently are the first step in
treating ASD. Approaches include a gluten and casein free diet, a rotation
diet, a specific carbohydrate diet, or a low oxalate diet. Gluten and casein
are proteins found in grains (especially wheat) and dairy, respectively. They
appear to be an issue of ASD children on two fronts. First, many children have
delayed-type hypersensitivity to these proteins—in essence, they are allergic to
them. Secondly, these proteins are broken down into intermediates that act like
opiates—altering behavior and contributing to the children’s separation from
their environment. Over 60% of ASD children improved with this diet alone based
on parent reporting. The rotation diet is based on a child’s individual food
sensitivities. We perform blood testing to determine a child’s sensitivity
profile and make recommendations on these results. The specific carbohydrate
diet can aid children that have issues with intestinal candidiasis (yeast) or
sugar sensitivities. The low oxalate diet can be helpful with children that
remain agitated despite other interventions or if there is any evidence of joint
problems. If this sounds overwhelming, don’t worry. We try to tailor a child’s
diet to his or her specific issues based on history, observation, and some
testing.
The second area of importance for children with ASD is the
arena of methylation and sulfation. These describe biochemical processes that
are essential for detoxification and energy production. Children with ASD
appear to be deficient in one or both of these areas. Because of this, they are
much more sensitive to environmental toxins than are unaffected children. If an
unaffected child is presented with an environmental toxin such as a pesticide
residue, their sulfation mechanisms with take care of the problem. A child with
ASD that has a problem with this system will be unable to process the same toxin
without causing other problems. The ASD child will have to “rob Peter to pay
Paul;” methylation and sulfation components will be stolen from energy
production in order to assist with detoxification. The net result will be a
cell that cannot function properly. The brain is particularly sensitive to this
process. If these changes occur in an adult, they will experience “brain fog”
and fatigue. If they occur in a child with a developing brain, they will result
in delayed or regressed development and behavioral problems. Treatment involves
identifying the toxins in the child’s environment, removal of those toxins from
both the environment and the child, and nutritional support to promote or
supplement these systems. Much of the biochemical testing we do at Bio Energy
is designed to identify these toxins and metabolic abnormalities.
A third area of concern with ASD children is the immune
system and the syndrome of chronic infections. Many ASD children have problems
with recurrent infections with strep or other common organisms. One recent
study demonstrated almost 60% of ASD children tested positive for Mycoplasma (a
common atypical bacterial infection) while only 5% of unaffected children tested
positive. A positive or negative result was based on the presence or absence of
the bacterial DNA in the child’s blood using an extremely sensitive technique
called PCR. There were similar results when these children were tested for
Chlymadia pneumonia and Human Herpes Virus 6. This would suggest that some part
of the ASD child’s immune system is not functioning properly. In addition, many
ASD children have abnormal stool cultures showing many potentially disease
causing (pathogenic) organisms as well as a lack of healthy bacteria. There are
a number of stool and blood tests that we perform to try to identify and treat
these organisms.
Another issue with ASD children is heavy metal treatment
with chelation. Many ASD children have elevated levels of lead, mercury, and
other toxic metals when tested appropriately. A large percentage of children
with ASD will show improvement with chelation (the process of removing these
metals using compounds that bind them and remove them from the body). Most
chelators we use also have the added benefit of being excellent supporters of
the sulfation processes we discussed earlier. At Bio Energy, we use both urine
challenge testing as well as hair analysis to determine who might benefit from
chelation therapy. Children that demonstrate issues with sulfation may also be
prescribed chelation in an effort to improve that function as well.
Finally, a word on “traditional” treatment of ASD. Nothing
we do at Bio Energy in the treatment of ASD is intended to replace the usual
PT/OT/Speech therapies of traditional medicine. At the end of the day, ASD
children have problems processing their environment. They need to be taught the
most basic issues of life, social interaction, and appropriate behavior. The
biomedical approaches are intended to allow this learning to occur, not replace
the process of teaching. The same is true of medications. We will do
everything we can to identify and correct reasons why a child is agitated and
misbehaving; however, sometimes medication is the only way for a child to calm
down enough to learn.
We strive to be thorough in our approach to the child with
ASD. This begins with parents filling out a thorough history of the child’s
development, history, and previous therapies that have been tried. We ask that
this be done a few weeks in advance of the initial evaluation so that Dr.
Neuenschwander can read it in advance. The actual appointment is scheduled for
two hours. This will allow Dr. Neuenschwander to get a complete history and
observe the child in action. Based on these ingredients, Dr. Neuenschwander
will recommend further testing and or dietary changes and supplements.

Take a look at this Autism Flyer for
more info.
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